Covid-19, a research by the Istituto Superiore di Sanità confirms that type I interferon can block the progression of the disease
A new weapon could arrive from Italy in the fight against Covid-19. Type I interferon (IFN), released by plasmacytoid dendritic cells (pDc) at the beginning of coronavirus infection, appears to elicit an immune response in the body that blocks the progression of the disease. The discovery comes from the joint work of a team of researchers (University of San Raffaele in Milan, Polyclinic of Tor Vergata, University of Padua, Metabolic Fitness Association) coordinated by the Istituto Superiore di Sanita ‘(ISS). The study published in Plos Pathogens analyzes precisely the mechanisms of innate immune responses in the pathogenesis of Covid-19.