• News
  • World
  • Economy
  • Society
  • Health
  • Sport
  • Culture
  • Techno
  • Science
The Gal Times
No Result
View All Result
No Result
View All Result
The Gal Times
No Result
View All Result

The vaccine race in China is difficult because of a shortage of patients

Nick Quaz by Nick Quaz
May 1, 2020
in Science
0
The vaccine race in China is difficult because of a shortage of patients

Vaccine production in China is challenging because the disease has subsided, making it impossible to conduct human trials in the infected area.

RelatedPosts

Archaeologist Rainer Kune discovered biblical city in Spain using satellite photos

Archaeologist Rainer Kune discovered biblical city in Spain using satellite photos

January 2, 2021

Science and its unexpected role in 2020 (and how to take advantage of this opportunity in Peru)

December 26, 2020
Santrich does not appear among those indicted in the case of drug trafficking and money laundering in the 2019 archive

Santrich does not appear among those indicted in the case of drug trafficking and money laundering in the 2019 archive

November 16, 2020

As the corona virus pandemic quickly swept continents, medical researchers around the world began an unprecedented race to find drugs and vaccines to fight the new disease.

The process usually takes years or even decades of laboratory research and testing has been shortened to just a few months to quickly control the virus strain that has infected more than 3 million people worldwide.

ADVERTISEMENT

Nine potential vaccine types have been tested in humans and more than 70 are undergoing clinical trials, according to the South China Morning Post. China has quickly joined the global effort, with 5 of the 9 vaccines developed by Chinese companies.

On the pharmaceutical front, testing of the anti-virus remdesivir by Gilead Science in the US showed that the results on April 29 could get urgent permission from the Food and Drug Administration. FDA).

But in China, two drug trials started in February were struggling due to a shortage of patients amid the outbreak of the disease in the country.

The vaccine race in China is difficult because of a shortage of patients

Vaccine preparation can take years, even decades. Photo: Xinhua.

Vaccine production in China faces a similar hurdle – the disease settles, it is almost impossible to conduct the third and final phase of human testing, according to industry insiders.

The third stage usually involved more than 1,000 volunteers – the group received the vaccine, and then compared this group with a group that received a placebo in a common infection area. This is the most important data to prove the vaccine is safe, effective and highly protective.

“It will be very difficult for all 32 vaccines (developed by Chinese vaccine manufacturers) and more than 100 types to be developed worldwide to complete every stage,” said Zhu Fengcai, deputy director of the Testing Center. Disease Control and Prevention Jiangsu Province, China, said at a seminar on vaccine preparation technology last week.

Zhu said his team is keen to bring vaccine testing to countries where the Covid-19 epidemic is still spreading to carry out the tests. This will quickly produce effective data under real-world conditions, he said.

Sinovac Biotech, which is also testing the Covid-19 vaccine, says controlling the pandemic in China poses a challenge to third-stage clinical trials, according to Theapers.cn.

Yang Xiaoming, chairman of China National Biotec Group, where two inactivated vaccines are being clinically tested at subsidiaries, said China was no longer suitable for the third phase of the testing process. He said other countries “where virus outbreaks are serious” have agreed to conduct experiments with this group.

But this approach also presents challenges.

“This requires countries with human resources who have experience in clinical trials, resources to respond to the Covid-19 epidemic and have the ability to monitor health, and are willing to cooperate with China,” he said. Zhu said.

Such tests also require approval from your local pharmaceutical and medical regulatory authority. In addition to these factors, the language barrier is also an issue, which Zhu’s team encountered when conducting clinical trials of the Ebola vaccine in Sierra Leone.

Richard Hatchett, executive director of the Alliance for Disease Prevention Initiative (CEPI), an organization that has funded nine separate corona virus vaccine projects in many countries, said China would need international cooperation. to help evaluate the potential vaccines.

“If China succeeds, these potential vaccines will need to be tested in other parts of the world where the virus is spreading,” he said.

“I think those companies are working with international partners like CEPI, like the Gavi vaccine alliance, like the World Health Organization (WHO) to see if their vaccines are rated as effective. not very important “.

The vaccine race in China is difficult because of a shortage of patients

The two Chinese companies are working with foreign companies to develop vaccines. Photo: SCMP

The WHO has launched the Solidarity Trial program to gather resources and data to accelerate development of safe and effective vaccines, including human trials.

A vaccine specialist who declined to be named said companies and governments should proactively find suitable locations for testing, rather than relying on WHO in such missions.

In addition to technical barriers, there are legal risks.

Overseas clinical trials for non-Chinese people are often not accredited by the Chinese drug regulatory authority, which means that vaccines cannot be properly registered, according to South. China Morning Post.

“Without the coordination and recognition of regulatory agencies’ third-stage clinical data, it would be very difficult for companies to spend such large amounts of money and take such risks at the stage trial. paragraph three, “said the expert.

“There are many (global) competitors and they may have a place to test because there is still a epidemic. Without the third phase test, the highest level of Chinese vaccines can be achieved is Conditional approval. Any progress that the Chinese vaccine has made will disappear. “

Two Chinese companies are cooperating with foreign companies to develop vaccines: Clover Biopharmaceuticals in Chengdu in cooperation with Australia, and Fosun Pharmaceutical in Shanghai in cooperation with Germany.

Meanwhile, Zhu at the CDC Jiangsu is thinking of a new way to find volunteers for human trials in China, including enlisting people returning from abroad.

But even that approach will not work at the moment because China still applies a 14-day isolation policy for Chinese entry.

“We believe this can be done but it will not be possible if the government does not relax the policies,” Zhu said.

Share Button

Related Posts

Archaeologist Rainer Kune discovered biblical city in Spain using satellite photos

Archaeologist Rainer Kune discovered biblical city in Spain using satellite photos

by Nick Quaz
January 2, 2021
0

German archaeologist Rainer Kune discovered an ancient city from biblical times in Spain. He studied satellite photos of a reserve...

Science and its unexpected role in 2020 (and how to take advantage of this opportunity in Peru)

by Nick Quaz
December 26, 2020
0

Less than a year after the start of the COVID-19 pandemic , there are already approved emergency vaccines and several...

Santrich does not appear among those indicted in the case of drug trafficking and money laundering in the 2019 archive

Santrich does not appear among those indicted in the case of drug trafficking and money laundering in the 2019 archive

by Nick Quaz
November 16, 2020
0

16.11.2020 10:08 Despite the fact that his name came up in the case of Iván Márquez's nephew for Drug Trafficking,...

What's the Big Difference Between Pfizer and Moderna COVID-19 Vaccines

What's the Big Difference Between Pfizer and Moderna COVID-19 Vaccines

by Nick Quaz
November 16, 2020
0

16.11.2020 10:08 The two American laboratories reported an efficiency of over 90% and are developed with the same technology, but...

The Moderna laboratory reported that its vaccine against COVID-19 has an efficacy of 94.5 percent

The Moderna laboratory reported that its vaccine against COVID-19 has an efficacy of 94.5 percent

by Nick Quaz
November 16, 2020
0

16.11.2020 08:08 The formula of the American pharmaceutical company also requires to be frozen, like that of Pfizer, but it...

A study says that COVID-19 was already circulating in Italy in September 2019, long before China recognized the existence of the virus

A study says that COVID-19 was already circulating in Italy in September 2019, long before China recognized the existence of the virus

by Nick Quaz
November 16, 2020
0

16.11.2020 07:08 Scientists from the National Cancer Institute in Milan pointed out that antibodies to the virus were already in...

COVID-19: How will we know that vaccines work and are safe?

COVID-19: How will we know that vaccines work and are safe?

by Nick Quaz
November 16, 2020
0

16.11.2020 01:41 It is not easy to determine its effectiveness. First, researchers need to know if simply giving someone an...

Fifteen viruses that have changed the history of mankind

Fifteen viruses that have changed the history of mankind

by Nick Quaz
November 16, 2020
0

16.11.2020 01:40 Pandemics, once they end, change some of our ways of relating to each other and introduce new customs...

Common Mutation May Make COVID-19 More Vulnerable to Vaccine, Study Warns

Common Mutation May Make COVID-19 More Vulnerable to Vaccine, Study Warns

by Nick Quaz
November 15, 2020
0

15.11.2020 23:08 While the mutated strain spreads faster, it is slightly more sensitive to drug neutralization of antibodies, said researchers...

NASA and SpaceX successfully launched historic manned mission to the International Space Station

NASA and SpaceX successfully launched historic manned mission to the International Space Station

by Nick Quaz
November 15, 2020
0

15.11.2020 21:08 A SpaceX Falcon 9 rocket with the Dragon capsule on top took off from Cape Canaveral, Florida November...

No Result
View All Result

Recommended

  • China has promised to make a vaccine for coronavirus available worldwide
  • China to test Sinovac vaccine in children and adolescents between 3 and 17 years of age this month
  • Coronavirus in Peru | Francisco Sagasti announces signing agreement with Sinopharm and AstraZeneca to purchase COVID-19 vaccine
  • India will test on humans a vaccine against coronavirus
  • Five rockets fired at US air base in Afghanistan
  • In Ukraine from the coronavirus test four drugs: list
  • The Chinese Covid-19 vaccine is less effective than previously reported.
  • It became known how much it would cost vaccines against coronavirus
  • Chinese volunteer for a vaccine who died from c …
  • Sinopharm's vaccine was applied to 100,000 workers at risk and also showed very promising results

Recent News

  • AFIP: Lawyers and accountants are revolting against a controversial base and awaiting fines
  • Bambita is isolated with a positive case of Coronavirus in her family: “She is waiting for the swab”
  • Wall Street suffered its worst decline in three months after the Fed announcement
  • Messi returns and the jewel he wasted in the end
  • At the start of vaccination campaigns, did vaccine manufacturers exhaust raw materials?
  • They analyze The Medium’s technical performance on Xbox Series X | S: Resolution, FPS, and more
  • Pediatric Industry Market Report with Key Country Data, Trends, CAGR Status, Stocks, Opportunities, and Growth Forecasts to 2026
Facebook Twitter

Categories

  • Culture
  • Economy
  • Health
  • News
  • Science
  • Society
  • Sport
  • Techno
  • World

© 2021 JNews - Premium WordPress news & magazine theme by Jegtheme.

No Result
View All Result
  • Contact us
  • Privacy Policy

© 2021 JNews - Premium WordPress news & magazine theme by Jegtheme.