The oil from rice bran is a source of monounsaturated fatty acids and gamma-oryzanol, which may help in reducing the blood lipid and oxidative stress. In this study, we investigated the effect of gamma-oryzanol on selected markers of blood.
Scientists from Mahidol University in Thailand studied whether the rice bran oil to enhance antioxidant activity in patients with hyperlipidemia. Previous experiments have shown that this oil can help lower lipid levels and oxidative stress due to its content of monounsaturated fatty acids and gamma-oryzanol. The team evaluated the biological activity of the latter, especially in relation to the lipid, antioxidant and inflammatory markers in the blood.
Characteristics of the study
The team investigated the 59 participants — all of them had hyperlipidemia. They were divided into four groups, namely: RBO1 (4000 units of gamma-oryzanol), RBO2 (8000 units of gamma-oryzanol), RBO3 (11,000 units of gamma-oryzanol) and the control (soybean oil).
Gamma oryzanol included in vegetable oil (30 ml per serving) that are used to prepare three cooked meals a day for four weeks.
The researchers took anthropometric measurements and blood samples to determine body weight and composition, as well as parameters of lipids, antioxidant status and markers of inflammation. This was done before and after the experiment.
Participants who had consumed rice bran oil, showed a significant reduction of cholesterol low-density lipoprotein (LDL) levels RBO2 and RBO3 11.8 and 12.2 percent, respectively. Scientists also revealed improved levels of antioxidants in individuals treated with RBO, compared to the control group.