AstraZeneca vaccine, Aifa: “On U-turn no contradiction, that’s why”

“The case of the ‘U-turn’ for the AstraZeneca anti-Covid vaccine initially recommended by Aifa only under the age of 55, subsequently extended up to the age of 65 and then after very rare side effects today only above the age of 60, for maximum caution, it may seem a contradictory decision but it is not contradictory “. This was stated by the director general of the Italian drug agency (Aifa) Nicola Magrini, in a short video, in which he explains why the indications for the use of drugs can change over time.

The AIFA CEO citing the AstraZeneca vaccine case recalls how the age indications given at the beginning depended on the fact that “we were able to clearly know that it worked, and quite well, in that particular age group, but – he reports – as new knowledge came, including these very rare but serious side effects, especially in younger populations, it became an unacceptable risk, given the availability of other vaccines that did not show these effects “.

“In medicine and in the research community – continues Magrini – we do not act only by consensus or only for studies always in the same direction but there are wide margins and degrees of freedom of interpretation of the various evidences. So – he concludes – the drastic changes must be seen positively and with confidence if they are based on the best available evidence. It must be acknowledged, digested and seen as a sign of continuous updating and progress of knowledge “.

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